PERINATAL MEDICINE 2008
A Joint Meeting of the
British Maternal and Fetal Medicine Society British Association of Perinatal Medicine The Neonatal Society Neonatal Nurses Association
British Maternal and Fetal Medicine Society British Association of Perinatal Medicine The Neonatal Society Neonatal Nurses Association


2nd - 4th June 2008
Harrogate International Centre
HARROGATE - UK
PROGRAMME

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MONDAY 2nd JUNE 2008
14.30 – 16.30 Registration  
16.30 – 16.45 Welcome Address
Professor Alan Cameron, President, British Maternal and Fetal Medicine Society (BMFMS)
Auditorium
SESSION 1 NEONATAL YOUNG INVESTIGATOR PRESENTATIONS
Chairs: Professor Andrew Whitelaw, President Neonatal Society (NNS)
Miss Tina Pollard, Chair, Neonatal Nurses Association (NNA)
 
16.45 – 17.10 NNA Draeger Scholarship Award Presentation
Managing the infant with necrotising enterocolitis post surgery, in preparation for transfer to the local hospital or to home
Mrs Anne Aspin
Nurse Consultant Neonatal Surgery, Leeds General Infirmary
 
17.10 – 17.50 NNS Young Investigator Presentation
The influence of birth weight and genotype on adipose tissue development:long term consequences for later obesity
Dr Alison Mostyn
Lecturer in Biological Sciences, School of Nursing, Nottingham University
 
SESSION 2 THE BAPM FOUNDERS’ LECTURE
Chair: Professor Neil Marlow, President, British Association of Perinatal Medicine (BAPM)
Auditorium
18.00 – 19.00 Placental insufficiency – will it be preventable by 2010?
Professor John Kingdom
Professor of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Canada
 
19.00 – 20.00 Welcome Reception Exhibition Hall

TUESDAY 3rd JUNE 2008
08.00 – 08.30 Registration  
SESSION 3 THE TIZARD LECTURE
Chairs: Professor Andrew Wilkinson (Oxford) and Mr Tim Overton (Bristol)
Vote of Thanks: Professor Howard Clark (Southampton)
Auditorium
08.30 – 09.30 Lung surfactant: protecting alveolar stability and sterility
Professor Sam Hawgood
Professor of Pediatrics, University of California, San Francisco, USA
 
09.30 – 10.00 The sequelae of assisted reproduction techniques
Professor Siladitya Bhattacharya
Professor in Reproductive Medicine, Aberdeen Maternity Hospital
 
10.00 – 10.30 Coffee, Exhibition and Poster Viewing Exhibition Hall

SESSION 4                 PARALLEL SESSIONS
10.30 – 12.30 SESSION 4A
BMFMS-FETAL MEDICINE
(Auditorium)

SESSION 4B
BAPM/NNS-BRAIN
(Queen’s Suite A)
SESSION 4C
NNA-POSTIVE PARENTING
(Queen’s Suite B)

SESSION 4A   BMFMS – FETAL MEDICINE
Chairs: Dr Gerald Mason (Leeds) and Dr Bill Martin (Birmingham)
Auditorium
10.30 – 11.15   Genetic imprinting
Professor Mark Hughes
Director, Genesis Genetics Institute, Director, Applied Genomics Technology Centre
Detroit, USA
 
11.15 – 11.25 4.1 Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and blood flow to the pregnant sheep uterus long-term
K. Abi Nader et al. (London)
 
11.25 – 11.35 4.2 Amniocentesis for soft markers - a six year review 2000-05
E. M. Knox et al. (Birmingham)
 
11.35 – 11.45 4.3 Fetal Troponin-T and pro-BNP in fetuses of Type 1 diabetic mothers
N. Russell et al. (Dublin, Ireland)
 
11.45 – 11.55 4.4 Three stage contingency screening for Down’s syndrome: the Stafford Pilot
J. Gardosi et al. (Birmingham)
 
11.55 – 12.05 4.5 DNA microarrays in the investigation of abnormal antenatal ultrasound – a prospective pilot study
K. E. Cohen et al (Leeds)
 
12.05 – 12.15 4.6 Gastroschisis in the UK: A prospective national study of prevalence, management and outcomes using obstetric, paediatric surgical and congenital anomaly reporting systems
M. Knight (Oxford)
 

SESSION 4B   BAPM/NNS – BRAIN
Chair: Dr Anoo Jain (Bristol)
Queen’s Suite A
10.30 – 10.45 4.7 Neonatal Resuscitation and Childhood Cognitive Outcomes
D. E. Odd et al. (Bristol)
 
10.45 – 11.00 4.8 Extremely preterm children at 11 years – how do they fare at school?
S. Johnson et al. (Nottingham)
 
11.00 – 11.15 4.9 Pattern and timing of brain injury on admission scans assessed using cranial ultrasound in infants with neonatal encephalopathy (NE) compared to low-risk infants in Mulago University Hospital, Kampala, Uganda
C. F. Hagmann et al. (London)
 
11.15 – 11.30 4.10 Proton magnetic resonance spectroscopy and the fetal brain in normally grown and growth restricted fetuses
L. Story et al. (London)
 
11.30 – 11.45 4.11 Treatment with cooling following perinatal asphyxia: Preliminary data from the UK TOBY Cooling Register
B. W. Strohm et al. (Oxford)
 
11.45 – 12.00 4.12 A randomised pilot feasibility study of therapeutic hypothermia for neonatal encephalopathy in a low resource setting in Equatorial Africa
N. J. Robertson et al. (London)
 
12.00 – 12.30
  Neuroprotection after hypothermia
Professor Pierre Gressens
Consultant in Paediatric Neurology, Robert Debre Hospital, Paris, France
 
SESSION 4C   NNA – POSTIVE PARENTING
Chairs: Mrs Sarah Kent (Northampton) and Mrs Dee Beresford (Nottingham)
Queen’s Suite B
10.30 – 11.05   Parenting programme – Development Care: a UK Vision
Mrs Chrissie Israel
Developmental Care Specialist Nurse, Southmead Hospital, Bristol
Ms Jane Abbott
Head of innovation BLISS, London
Dr Ezam MatAli
Consultant Neonatologist, Northwick Park Hospital, Harrow
 
11.15 – 12.15   How many mountains can they climb?
Mr Ian Woodroffe
Counsellor Psychological Support Neonatal Services, Addenbrookes Hospital, Cambridge
 
12.15 – 12.30   A Critical Incident Reporting System (CIRS) and an analysis of critical incidents in a Level 3 NICU
J.A. Foy et al. (Newport)
 
12.30 – 14.00   Lunch, Exhibition and Poster Viewing Exhibition Hall

13.00 – 14.00 LUNCHTIME NEONATAL POSTER WALKS Level 5
13.00 – 13.50 LUNCHTIME MEET THE EXPERTS SESSIONS  
  A. Big mums and big babies
Dr Siohban Quenby (Liverpool) & Dr Tracey Johnston (Birmingham)
Queen’s Suite A
  B. Shoulder dystocia
Dr Tim Draycott (Bristol) & Dr Mike Geary (Dublin, Ireland)
Conference Suite
  C. Genetics – New techniques for the 21st Century
Professor Mark Hughes (Detroit, USA)
Queen’s Suite B
  D. Fetal & long term consequences of ventriculomegaly
Dr Stephen Sturgiss (Newcastle upon Tyne) & Miss Maria Cartmill (Nottingham)
Auditorium

SESSION 5 FETAL GROWTH RESTRICTION
Chairs: Professor Steve Robson (Newcastle upon Tyne) and Dr Helen Budge (Nottingham)
Auditorium
14.00 – 14.30 Is catch up growth good for you?
Dr Jonathan Wells
Reader in Pediatric Nutrition, Institute of Child Health, London
 
14.30 – 15.00 Does fetal growth restriction affect long term neurocognitive outcomes?
Professor Neil Marlow
Professor of Neonatal Medicine, Queen’s Medical Centre, Nottingham
 
15.00 – 15.30 Tea, Exhibition and Poster Viewing Exhibition Hall

SESSION 6                  PARALLEL SESSIONS
15.30 – 17.00 SESSION 6A
BMFMS-PREGNANCY OUTCOME
(Auditorium)
SESSION 6B
BAPM/NNS-LUNGS & INFECTION
(Queen’s Suite A)
SESSION 6C
NNA-DEVELOPMENTAL CARE
(Queen’s Suite B)

SESSION 6A   BMFMS – PREGNANCY OUTCOME
Chairs: Dr Richard Smith (Norwich) and Mr Myles Taylor (Exeter)
Auditorium
15.30 – 16.00   Older Mothers
Dr Susan Bewley
Consultant Obstetrician, St. Thomas’ Hospital, London
 
16.00 – 16.10 6.1 The relation between social deprivation and stillbirth causes
A. Tang et al. (Liverpool)
 
16.10 – 16.20 6.2 Adverse perinatal outcomes and risk factors for pre-eclampsia in women with chronic hypertension: a prospective study
L. C. Chappell et al. (London)
 
16.20 – 16.30 6.3 Teenage pregnancy and micronutrient status. a study of 500 pregnant teenagers from 2 UK inner city populations (The ATE study)
L. Poston et al. (London)
 
16.30 – 16.40 6.4 Maternal obesity and the risk of stillbirth in small-for-gestational age babies identified by customised birthweight centiles
J. Gardosi et al. (Birmingham)
 
16.40 – 16.50 6.5 Maternal and obstetric associates of being in good condition following singleton extremely preterm birth
Z. Alfirevic et al. (Liverpool)
 
SESSION 6B BAPM/NNS – LUNGS & INFECTION
Chair: Dr Bryan Gill (Leeds)
Queen’s Suite A
15.30 – 15.45 6.6 A randomised comparison of wide versus narrow saturation monitor alarm limits for controlling oxygen therapy in preterm infants
S.S. Bhushan et al. (Edinburgh)
 
15.45 – 16.00 6.7 Comparison of left and right ventricular function in term and preterm neonates using tissue doppler imaging
R.J.S. Negrine et al (Birmingham)
 
16.00 – 16.15
6.8 Low cord blood monocytes mhc class II expression is associated with sepsis in term and preterm neonates
M. Azizia et al. (London)
 
16.15 – 16.30 6.9 Ureaplasma spp. or bacterial colonisation are associated with the development of chronic lung disease of prematurity
N.C. Maxwell et al. (Cardiff)
 
16.30 – 17.00   Long term respiratory outcome of premature birth – are we making it worse?
Professor Anne Greenough
Professor of Neonatology and Clinical Respiratory Physiology, King’s College London
 
SESSION 6C   NNA – DEVELOPMENTAL CARE
Chair: Miss Tina Pollard, Chair, Neonatal Nurses Association
Queen’s Suite B
15.30 – 16.30   Perinatal neuroscience and skin-to-skin contact
Dr Nils Bergman
Consulting Public Health Physician, Cape Town, South Africa
 
16.30 – 16.45 6.10 Neonatal nurses’ attitudes towards extremely low gestation infants
K. Gallagher et al. (Nottingham)
 
16.45 – 17.00 6.11 ‘The promise of catch-up’: maternal expectations regarding the notion of ‘catch up’ in the development of prematurely born infants
S.V. Manns (Bristol)
 
17.00 – 18.00   AGM for BMFMS Auditorium
19.30 – 23.00   Conference Reception and Dinner , Old Swan Hotel, Harrogate  

WEDNESDAY 4th JUNE 2008

08.30 – 09.00 Registration  
SESSION 7 PERINATAL INFLAMMATION
Chairs: Professor Alan Cameron (Glasgow) and Dr Jag Ahluwalla (Cambridge)
Auditorium
09.00 – 09.40
BMFMS SOCIETY LECTURE
Professor Steve Thornton
Professor of Obstetrics, University of Warwick and University Hospital Coventry
 
09.40 – 10.20 Perinatal inflammation and central nervous system injury
Professor Olaf Dammann
Research Professor, Tufts University, Director of Clinical Research, Newborn Medicine
Floating Hospital for Children, Boston, USA

 
10.20 – 10.50 Coffee, Exhibition and Poster Viewing Exhibition Hall

SESSION 8                  PARALLEL SESSIONS
10.50 – 12.30 SESSION 8A
BMFMS-MATERNAL MEDICINE

(Auditorium)
SESSION 8B
BAPM/NNS-RESUSCITATION/
EARLY CARE/PREMATURITY
(Queen’s Suite A)
SESSION 8C
NNA-FEEDING DIFFICULTIES

(Queen’s Suite B)

SESSION 8A   BMFMS – MATERNAL MEDICINE
Chairs: Professor Fionnuala McAuliffe (Dublin) and Dr Margaret Ramsay (Nottingham)
Auditorium
10.50 – 11.20   Type II diabetes in pregnancy
Mr Andrew Dawson
Consultant Obstetrician, Nevill Hall Hospital, Gwent Healthcare NHS Trust, Abergavenny
 
11.20 – 11.50   Pre-Eclampsia
Dr Michael Belfort
Director of Perinatal Research and Fetal Therapy, HCA, Nashville Tennessee and Professor of
Obstetrics and Gynaecology, Salt Lake City, USA
 
11.50 – 12.00 8.1 Vascular endothelial growth factor165b and pre-eclampsia
V.L. Bills et al. (Bristol)
 
12.00 – 12.10 8.2 Haemodynamic and placental markers to predict pre-eclampsia
A. Khalil et al. (London)
 
12.10 – 12.20 8.3 Minimally invasive haemodynamic monitoring accurately demonstrates the profound cardiovascular effects of 5 units syntocinon bolus at caesarean section
A. Carlin et al. (Liverpool)
 
12.20 – 12.30 8.4 Hyperemesis in pregnancy study: an RCT of midwife-led ‘outpatient’ care
C. McParlin et al. (Newastle upon Tyne)
 
SESSION 8B   BAPM/NNS – RESUSCITATION/EARLY CARE/PREMATURITY
Chair: Professor David Field (Leicester)
Queen’s Suite A
10.50 – 11.05 8.5 EPICure 2: Interventions to stabilise extremely preterm babies at birth
K. Costeloe et al. (London)
 
11.05 – 11.20
8.6 Sex-specific differences in circulating carbon monoxide and the increased incidence of hypotension in male preterm infants
M.J. Stark et al. (Newcastle, Australia)
 
11.20 – 11.35 8.7 Predicting neonatal mortality: a comparison of the CRIB-II score with and without temperature at admission
B.N. Manktelow et al. (Leicester)
 
11.35 – 11.50
8.8 The BLISS cluster randomised controlled trial of the effect of ‘Active Dissemination of Information’ on standards of care for premature babies in England (BEADI)
D. Elbourne et al. (London)
 
11.50 – 12.30   Patterns of outcome at borderline viability
Professor Kate Costeloe
Professor of Paediatrics, Homerton Hospital NHS Foundation Trust, London
 
SESSION 8C   NNA – FEEDING DIFFICULTIES
Chair: Mrs Ruth Moore, Vice Chair, Neonatal Nurses Association
Queen’s Suite B
10.50 – 11.50   Supporting preterm breast feeding
Ms Anne Aloysius
Specialist Speech and Language Therapist, Queen Charlottes and Chelsea Hospital, London
Ms Liz Jones
MPhil, Registered Nurse, Registered Midwife, University Hospital of North Staffordshire,
Stoke-on-Trent

 
11.50 – 12.15   Impact of prebiotic supplementation in preterm nutrition
Professor Walter A. Mihatsch
Associate Professor at Ulm University and Head of Department of Paediatrics,Schwäbisch Hall Deaconry Hospital, Germany
 
12.15 – 12.30 8.9 Nasal injuries in preterm infants associated with CPAP
E.A. Alsop et al. (Middlesbrough)
 
12.30 – 14.00
  Lunch, Exhibition and Poster Viewing Exhibition Hall

13.00 – 14.00 BMFMS/NEONATAL POSTER PRIZE PRESENTATION WALKS Level 5
13.00 – 13.50 LUNCHTIME MEET THE EXPERTS SESSIONS  
  E. Pre-eclampsia
Dr Michael Belfort (Salt Lake City, USA) & Dr Steve Yentis (London)
Queen’s Suite A
  F. Fetal & neonatal consequences of premature rupture of membranes
Dr Alison Bedford-Russell (Birmingham) & Dr Sarah Vause (Manchester)
Auditorium
  G. Optimising neonatal intensive care unit transfer
Dr Andy Leslie (Notingham) & Dr Steve Kempley (London)
Conference Suite
  H. Hypothermia as a standard of care
Professor Malcom Levene (Leeds) & Dr James Tooley (Bristol)
Queen’s Suite B

SESSION 9                     PARALLEL SESSIONS
14.00 – 15.30 SESSION 9A
BMFMS-LABOUR & DELIVERY
(Auditorium)
SESSION 9B
BAPM/NNS-NUTRITION
(Queen’s Suite A)
SESSION 9C
NNA-SURGICAL INTERVENTIONS
(Queen’s Suite B)

SESSION 9A   BMFMS – LABOUR & DELIVERY
Chairs: Dr Lucy Kean (Nottingham) and Dr Tracey Johnston (Birmingham)
Auditorium
14.00 – 14.10 9.1 Myometrial contractility studies in diabetic pregnant women
S. Alqahtani et al. (Liverpool)
 
14.10 – 14.20 9.2 A physiological approach to stimulating labour: PULSE a randomised controlled trial of pulsatile versus continuous oxytocin administration
R.M. Tribe et al. (London)
 
14.20 – 14.30 9.3 Resident obstetric consultant cover: does it make a difference to the vaginal delivery rates or perinatal morbidity?
A. Green et al. (Nottingham)
 
14.30 – 14.40 9.4 The effect of Barusiban on plasma concentrations and uterine contractility in threatened preterm labour: a randomised, double-blind, placebo-controlled trial
S. Thornton et al. (Coventry)
 
14.40 – 14.50 9.5 Changing trends in peripartum hysterectomy over the last four decades
K. Flood et al. (Dublin, Ireland)
 
15.00 – 15.30   Past, present and future of fetal monitoring in labour
Professor Gerald H.A. Visser
Professor of Obstetrics, Head of Department University Medical Centre, Utrecht, The Netherlands
 
SESSION 9B   BAPM/NNS – NUTRITION
Chair: Dr Alison Leaf (Bristol)
 
14.00 – 14.15
9.6 Differential effects of maternal nutrient restriction on inflammation in renal and adipose tissue in obese juvenile offspring – the role of TLR4 and CCR2
D. Sharkey et al. (Nottingham)
 
14.15 – 14.30 9.7 The effect of caesarean section and a single enteral feed on liver metabolism in response to total parenteral nutrition
M. J. Hyde et al. (London)
 
14.30 – 15.00   How fast should we make preterm babies grow?
Professor Neena Modi
Professor of Neonatal Medicine, Imperial College London
 
15.00 – 15.15 9.8 Does postnatal (PN) growth affect post-discharge morbidity in preterm infants?
S. T. Dharmaraj et al. (Newcastle upon Tyne)
 
15.15 – 15.30 9.9 The EPICure Study: longitudinal growth measurements over an 11 year follow up period
J. A .Fawke et al. (Nottingham)

 
SESSION 9C   NNA – SURGICAL INTERVENTIONS
Chair: Mrs Jackie Stretton (Solihull)
Queen’s Suite B
14.00 – 14.35   Surgical management of necrotising enterocolitis
Mr Naved Alizai
Consultant Paediatric Surgeon, Leeds General Infirmary
 
14.35 – 15.00 9.10 First impressions: the experiences and perceptions of fathers of their first visit to the neonatal unit
M. E. Harvey et al. (Birmingham)
 
15.05 – 15.30 9.11 Nursing workload in UK tertiary neonatal units
D. W. A. Milligan et al. (Newcastle upon Tyne)
 
15.30 – 15.45   Session break  
SESSION 10   DISCUSSION: ‘HAS PATIENT CHOICE GONE TOO FAR?’ VIEWS FROM OTHER DISCIPLINES
Chairs: Professor Neil Marlow (Nottingham) & Professor Alan Cameron (Glasgow)
Auditorium
15.45 – 16.45   Caesarean section
Lead Speaker: Dr Ray Noble
Senior Lecturer in Medical Ethics, University College London

Borderline viability
Lead Speaker: Professor David Archard
Professor of Philosophy and Public Policy, Furness College, Lancaster
 
16.45 – 17.00   Presentation of Prizes  
17.00   Close of Meeting